Recent Publications
Nanes BA, Chiasson-MacKenzie C, Lowery AM, Ishiyama N, Faundez V, Ikura M, Vincent PA, and Kowalczyk AP. 2012. p120-catenin binding masks an endocytic signal conserved in classical cadherins. J. Cell Biol, 199(2):365-80.
Saito M, Caughman CY, Mao X, Stahley SN, Tucker DK, Payne AS, Amagai M, Kowalczyk AP. 2012. Signaling Dependent and Independent Mechanisms in Pemphigus Vulgaris Blister Formation. PLoS One. Vol. 7(12):e50696 .
Oas RG, Nanes BA, Esimai CC, Vincent PA, García AJ, Kowalczyk AP. 2013 p120-catenin and β-catenin differentially regulate cadherin adhesive function. Mol Biol Cell. Vol. 24(6):704-14.
Tucker DK, Stahley SN, and Kowalczyk AP. 2014. Plakophilin-1 protects keratinocytes from pemphigus vulgaris IgG by forming calcium-independent desmosomes. J Invest Dermatol. Vol. 134(4):1033-43.
Stahley SN, Saito M, Faundez V, Koval M, Mattheyses AL, Kowalczyk AP. 2014. Desmosome assembly and disassembly are membrane raft-dependent. PLoS One. Vol. 9(1):e87809.
Stahley SN, Warren MF, Feldman RJ, Swerlick RA, Mattheyses AL, Kowalczyk AP. 2016. Super resolution microscopy reveals altered desmosome organization, endocyto sis and desmosome splitting in pemphigus vulgaris epidermis. J Invest Dermatol. Vol. 136(1):59-66.
Cadwell CM, Jenkins PM, Bennett V, Kowalczyk AP. 2016. Ankyrin-G Inhibits Endocytosis of Cadherin Dimers. J. Biol. Chem. 8;291(2):691-704.
Stahley SN, Bartle EI, Atkinson CE, Kowalczyk AP, Mattheyses AL. 2016. Molecular organization of the desmosome as revealed by direct stochastic optical reconstruction microscopy. J. Cell Science. Vol. 129(15):2897-904.
Roberts BJ, Svoboda RA, Overmiller AM, Lewis JD, Kowalczyk AP, Mahoney MG, Johnson KR, Wahl JK. 2016. Palmitoylation of Desmoglein 2 is a Regulator of Assembly Dynamics and Protein Turnover. J. Biol. Chem. Vol. 291(48):24857-24865.
Nanes BA, Myers CM, Cadwell CM, Robinson BS, Lowery AM, Vincent PA, Mosunjac M, Früh K, and Kowalczyk AP. 2017. p120-catenin regulates VE-cadherin endocytosis and degradation induced by the Kaposi Sarcoma associated ubiquitin ligase K5. Mol. Biol. Cell. Vol. 28(1):30-40.
Su, W and Kowalczyk, AP. 2017. The VE-cadherin cytoplasmic domain undergoes proteolytic processing during endocytosis. Mol. Biol. Cell. Vol. 28(1):76-84.
Shafraz O, Rübsam M, Stahley SN, Caldara AL, Kowalczyk AP, Niessen CM, Sivasankar S1. 2018. E-cadherin binds to desmoglein to facilitate desmosome assembly. Elife. Jul 12;7. pii: e37629. doi: 10.7554/eLife.37629.
Lewis JD, Caldara, AL, Zimmer SE, Stahley SN, Seybold A, Strong NL, Frangakis AS, Levental I, Wahl III JK, Mattheyses AL, Sasakii T, Nakabayashij K, Hataj K, Matsubaraj Y, Ishida-Yamamotok A, Amagai M , Kubo A, Kowalczyk AP. 2019. The Desmosome is a Mesoscale Lipid Raft-Like Membrane Domain. Mol. Biol. Cell. Vol. 30(12):1390-1405.
Cho A, Caldara AL, Ran NA, Menne1 Z, Kauffman RC, Affer M, Llovet A, Norwood C, Scanlan A, Mantus G, Bradley B, Zimmer S, Schmidt T, Hertl M, Payne AS, Feldman R, Kowalczyk AP, and Wrammert J. 2019. Single-cell analysis suggests that ongoing affinity maturation drives the emergence of pemphigus vulgaris autoimmune disease. Cell Reports. Vol. 28(4):909-922.
Grimsley-Myers CM, Cadwell CM, Isaacson RH, Campos J, Hernandes MS, Seo T, Giang W, Griendling KK, Kowalczyk AP. 2020. VE-cadherin endocytosis controls vascular integrity and patterning during development J. Cell Biol. May 4;219(5):e201909081. doi: 10.1083/jcb.201909081
Bartle EI, Urner TM, Rao TC, Kowalczyk AP, Mattheyses AL. 2020. Protein mobility regulates calcium independence of epithelial junctions. J. Cell Biol. Jun 1;219(6):e201906153. doi: 10.1083/jcb.201906153